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Management Plan for Stage II Liver Cancer – TACE Approach

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  • Management Plan for Stage II Liver Cancer – TACE Approach

1. Initial Consultation & Evaluation

  • Comprehensive assessment by a hepatobiliary surgeon and interventional radiologist.
  • Review of medical history, liver function, and overall health status.
  • Discussion of treatment options, including TACE and potential surgical intervention if feasible.

2. Medical Records Review & Pre-Treatment Assessment

  • Detailed analysis of prior imaging, laboratory tests, and treatment history.
  • Evaluation of liver function using Child-Pugh Score and ALBI score to assess treatment tolerance.

3. Laboratory Investigations

  • Complete blood count (CBC)
  • Liver function tests (LFTs)
  • Renal function panel
  • Coagulation profile
  • Tumor markers (Alpha-Fetoprotein – AFP)
  • Hepatitis B and C serology (if applicable)

4. Pre-Treatment Imaging

  • Contrast-enhanced CT scan or MRI of the liver to assess tumor size, vascular invasion, and suitability for TACE.
  • Angiographic assessment to map hepatic artery anatomy.
  • Additional PET scan if metastatic disease is suspected.

5. Multidisciplinary Tumor Board Discussion

Case review by a team of hepatobiliary surgeons, interventional radiologists, and oncologists.

Decision on treatment strategy:
  • TACE as primary treatment (if surgery is not feasible).
  • TACE as neoadjuvant therapy (prior to surgery or liver transplantation).

6. Pre-TACE Preparation

  • Patient education regarding the procedure, risks, and expected outcomes.
  • Pre-procedure hydration and renal function optimization.
  • Antibiotic prophylaxis if required.
  • Temporary discontinuation of anticoagulants if applicable.

7. Transarterial Chemoembolization (TACE) Procedure

  • Patient transferred to the interventional radiology suite.
  • Local anesthesia with conscious sedation or general anesthesia if indicated.
  • Catheter insertion via femoral artery, advanced into the hepatic artery.
  • Selective embolization of tumor-feeding arteries using chemotherapy (individual selection of chemotherapy) mixed with embolic agents.
  • Post-procedure angiography to confirm successful embolization.

8. Immediate Post-TACE Monitoring

  • Patient observed in the post-procedure recovery unit for 4–6 hours.
  • Pain management with analgesics and antiemetics for post-embolization syndrome.
  • Monitoring of vital signs, liver enzymes, and kidney function.

9. Hospital Stay & Recovery

  • Observation for 24–48 hours if needed, especially in patients with compromised liver function.
  • Gradual resumption of diet and mobility.
  • Post-TACE syndrome management (fever, nausea, right upper quadrant pain).

10. Follow-Up & Response Assessment

  • First imaging follow-up (CT/MRI) in 4–6 weeks to assess tumor response.
  • Repeat AFP measurement to monitor treatment effectiveness.
  • Consider repeat TACE if incomplete tumor response.

11. Long-Term Monitoring & Next Steps

  • Regular imaging every 3 months to assess for recurrence or progression.
  • Evaluation for surgical resection or liver transplantation if tumor burden is reduced.
  • Discussion of systemic therapy (e.g., tyrosine kinase inhibitors like sorafenib) if disease progresses.

💡Important for You

WEGOVITA offers medical coordination services by connecting international patients with top hospitals and specialists across Germany. We support access to expert evaluations, facilitate treatment logistics, and present a range of available medical options.

However, WEGOVITA does not provide direct medical treatment, make medical diagnoses, or recommend specific therapies. All final medical decisions—including diagnosis, treatment planning, and cost—are made solely by licensed medical professionals after a full clinical assessment of the individual patient.

This information is provided for informational purposes, based on internationally recognized guidelines and practices used in Germany’s leading medical institutions. It is not a substitute for professional medical advice.

💡 Interested in clinical trial references, treatment innovations, or cost comparisons? Contact our medical coordination team at info@wegovita.com for personalized assistance.

Your Health. Your Journey. With WEGOVITA.